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METHOTREXATE

METHOTREXATE

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NAME :- METHOTREXATE

IUPAC NAME :- (2S)-2-[(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioic acid

CAS NO. :- 59-05-2

FORMULA :- C20H22N8O5

SYNONYMS :- METHOTREXATE;METHYLAMINOPTERIN;METHYLAMINOPTERINE;ANTIFOLAN;L-(+)-AMETHOPTERIN;4-AMINO-N 10-METHYLPTEROYL-L-GLUTAMIC ACID;4-AMINO-10-METHYLPTEROYLGLUTAMIC ACID;(+)-4-AMINO-10-METHYLFOLIC ACID

APPLICATION :- A deuterated folic acid antagonist

DESCRIPTION :- An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.