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L- SELENOMETHINONINE

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L- SELENOMETHINONINE
L- SELENOMETHINONINE
Price And Quantity
  • Kilograms/Kilograms
  • 20
  • , Kilograms/Kilograms
  • 58000 INR
    Product Specifications
    • L-SELENOMETHINONINE
    • Powder
      Product Description

      NAME :- L-SELENOMETHIONINE


      IUPAC NAME :- 2-Amino-4-methylselanyl-butanoic acid


      CAS NO. :- 3211-76-5


      FORMULA :- C5H11NOSE


      SYNONYMS :- (S)-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID;(S)-2-AMINO-4-(METHYLSELENO)BUTYRIC ACID;SEMET;SELENOMETHIONINE, L-(+)-;SELENO-L-METHIONINE;L-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID;L-(+)-SELENOMETHIONINE;L-SELENOMETHIONINE


      APPLICATION :- A compound shown to increase expression of glutathione peroxidase


      DESCRIPTION :-  L-Selenomethionine displays antioxidant activity and has been shown to increase the activity of glutathione peroxidase in endothelial cells. Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks, mutations and interference with protein tyrosine-based signaling and other protein functions due to formation of 3-nitrotyrosine, caused by excessive peroxynitrite. L-Selenomethionine administration to cancer cell lines (MCF-7/S breast carcinoma, DU-145 prostate cancer cells and UACC-375 melanoma) results in apoptotic cell death and aberrant mitosis. These human tumor cell lines exhibited dose-dependent growth inhibition by L-Selenomethionine in the micromolar range (45 to 130 M), while growth inhibition of normal fibroblasts required 1 mM L-Selenomethionine.


      Trade Information
      • 500 Per Day
      • 1 Days
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