Pharmaceutical Pellets

Pantoprazole Sodium Pellets are available as white-colored pellets and mainly used in the treatment of peptic ulcers. Their chemical formula is C16H14F2N3NaO4S and the IUPAC name is sodium 5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl) methylsulfinyl] benzimidazol-1-ide. These pellets are prepared by fluid bed coating technology in which there is a direct compression of the enteric-coated pellets and suitable excipients. They are sold by different brand names such as Somac, Pantoloc, Protium, Pantecta, Protonix, and Pantohea.

The IUPAC name of Esomeprazole Magnesium Pellets is magnesium; 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl) methylsulfinyl] benzimidazol-1-ide; 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl) methylsulfinyl] benzimidazol-1-ide. They have the chemical formula C34H42MgN6O9S2 and the molar mass is 767.168 g/mol. These are the magnesium salt of esomeprazole and has the property of gastric proton pump inhibition. They perform their function by developing one or more covalent disulfide bonds with proton pump thereby restricting its activity and there is no secretion of H+ ions into the gastric lumen.